News and Articles on Health. Medical research topics.

The men of any age may develop breast cancer, but is usually detected in men between 45 and 65 years of age. Breast cancer found in men is less than 1% of all cases of breast cancer. Although rare, the inflammatory breast cancer found in males is a very aggressive cancer that grows quickly. It’s called inflammatory because cancer cells block the lymph vessels and this is manifested in the skin, which becomes thick and hollowed, the appearance is similar to that of an orange peel.

You may find the following types of breast cancer in males:

• Infiltrating ductal carcinoma: Cancer that has spread beyond the cells lining the breast ducts. This is the kind suffered by the majority of men with breast cancer.
• Ductal carcinoma in situ: Abnormal cells found in the lining of a duct, also called intraductal carcinoma.
• Inflammatory breast cancer: A type of cancer in which the breast looks red and swollen and feels warm.
• Paget’s disease of the nipple: the surface of an underlying tumor ducts underneath the nipple.

Inflammatory breast cancer can spread in just a few weeks, is often mistaken for other things like a rash or infection. The symptoms are:

• Redness, swelling and warmth in the breast
• Red skin, purple or bruised
• Skin with bumps and / or marks as an orange
• Burning, pain and tenderness
• Increased breast size and an inverted nipple

Because usually this cancer does not form like a regular ball of tissue, but it spreadsthroughout the breast tissue right a way. This is why it is very difficult to detect with a mammogram alone, and the magnetic resonance imaging and biopsies can not usually diagnose it accurately either. However, surgical biopsy and positron emission tomography (PET) can be used effectively to detect it. In the near future, PET may be the most important diagnostic test for the inflammatory breast cancer. Although still under evaluation, Doctors have found that PET is able to see more inflammatory breast cancer, including lymph nodes removed from the breast, which will determine the presence of metastases at diagnosis better than other test.

Certain factors affect prognosis (chance of recovery) and treatment options. 
The prognosis and treatment options depend on the following aspects:

• The stage of cancer (if located in the breast only or has spread to other parts in the body).
• The type of breast cancer.
• The concentration of estrogen receptors and progesterone receptors in tumor tissue.
• If cancer is also found in the other breast also.
• The age and general health of the patient.

I hope that you find this informayion helpful.

Breast cancer can spread to any part of your body through the blood and lymphatic system. The metastasis of breast cancer cells is what makes the disease very dangerous. Metastasis means the cancer cells have traveled from the place of origin, i.e. the breast, to other parts of the body.

When the cancer cells travel from the breast to the underarm lymph nodes, it is still considered to be early stages of breast cancer and it has a high potential to be completely cured. With surgery and treatment there is a very high chance that all the disease can be completely eradicated from the body.

When the cancer cells travel beyond the lymph nodes to other distant parts of the body, the patient is said to have distant metastasis. The bones, lungs and liver are the most commonly affected places in the body that breast cancer cells spread to. Though treatment is available for breast cancer and for metastasic breast cancer, once the cancer has traveled beyond the breast and underarm lymph nodules, it can no longer be totally cured.

Scientists have recently discovered a molecule that could be the main reason behind the spreading of breast cancer cells to different parts of the body. The molecule known as Brk is found in almost 60% of breast cancers and they accelerate the growth of the tumor cells, encouraging metastasis to other parts of the body.

The study was conducted on breast cancer patients who had extremely poor responses to the treatments. The Brk molecule was found in very high concentration in these patients, which means that not only does it cause the cancer to grow more aggressively; it also encourages its rapid spread to other parts of the body.

The study also came out with another crucial finding. The tumor cells died when the Brk molecule was inhibited, but the cancer cells re-emerged when the molecule was introduced again. This points to a significant level of involvement that the Brk molecule has in encouraging the breast cancer cells to survive, grow and spread.

Scientists are currently studying how exactly the Brk molecule promotes the growth of breast cancer cells so that they can develop ways to prevent that from happening. The findings are quote encouraging and shed new light on the age old battle of mankind against cancer.